서브비주얼

교수진소개

김한솔 프로필 사진
  • 성명

    김한솔 교수

  • 전공

    단백질공학/생물의약품

  • 최종학위

    울산과학기술원 이학박사

  • 연구실

    PRIME의생명공학관(J동) 307호

  • 연락처

    055-320-3465

  • 이메일

    hsk@inje.ac.kr

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학력

(박사)울산과학기술원 생명과학과

교육 및 연구경력

· Ph.D., Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST)

· Postdoctoral fellow, Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST)

· Visiting Scholar, Department of Bioengineering, University of California, Berkeley (UC Berkeley)

· Postdoctoral fellow, Department of Bioengineering, University of California, Berkeley (UC Berkeley)

연구 관심 분야

· Targeted Drug Delivery System, Intracellular delivery of therapeutics, Protein-based Theragnostic Systems

· Gene therapeutics

· Nanobiotechnology and Protein engineering

· Biosensing & Imaging

강의 분야

· 병원미생물학 (Microorganisms)

· 생물의약품학 (Biopharmaceuticals)

· 의약품분석학 (Pharmaceutical analysis)

저서 및 주요 논문

1. Li, J., Tuma, J., Han, H., Kim, H., Wilson, R., Lee, H.Y. & Murthy, N., The Coiled-Coil Forming Peptide (KVSALKE)5 is A Cell Penetrating Peptide that Enhances the Intracellular Delivery of Proteins. Advanced Healthcare Materials, 2021, p.2102118

2. Choi, H., Eom, S., Kim, H., Bae, Y., Jung, H. S., and Kang, S., Load & Display: Engineering Encapsulin as a Modular Nanoplatform for Protein-cargo Encapsulation and Protein-ligand Decoration Using Split Intein and SpyTag/SpyCatcher. Biomacromolecules, 2021, DOI:10.1021/acs.biomac.1c00481

3. Kim, H.*, Jin, S.*, Choi, H., Kang, M., Park, SG., Jun, H., Cho, H., and Kang, S., Target-switchable Gd(III)-DOTA/protein cage nanoparticle conjugates with multiple targeting affibody molecules as target selective T1 contrast agents for high-field MRI. Journal of Controlled release, 2021, 335, 269-280.

4. Kim, H., Choi, H., Bae, Y., and Kang, S., Development of Target-Tunable P22 VLP-Based Delivery Nanoplatforms Using Bacterial Superglue. Biotechnol. Bioeng., 2019, 116, 2843-2851. *Editor's Choice Article.

5. Oh, J. Y*, Kim, H.*, Palanikumar, L.*, Go, E. M., Jana, B., Park, S. A., Kim, H. Y., Kim, K., Seo, J. K., Kwak, S. K., Kim, C., Kang, S., and Ryu, J-H., Cloaking Nanoparticles with Protein Corona Shield for Targeted Drug Delivery. Nat. Comm., 2018, 9, 4548.

6. Kim, H.*, Kang, Y. J.*, Min, J., Choi, H. and Kang, S. Development of an Antibody-binding Modular Nanoplatform for Antibody-guided Targeted Cell Imaging and Delivery. RSC Adv., 2016, 6, 19208-19213. 

7. Choi, B., Kim, H., Choi, H., and Kang, S., Protein Cage Nanoparticles as Delivery Nanoplatforms. Adv. Exp. Med. Biol. 2018, 1064, 27-43.

8. Choi, H., Choi, B., Kim, H., Kim, G. J., Kim, H., Jung, H. S., and Kang, S., Fabrication of Nano-reaction Clusters with Dual-functionalized Protein Cage Nano-building Blocks. Small, 2018, 14, 1801488.

9. Bae, Y., Kim, G.J., Kim, H., Park, S.G., Jung, H.S., and Kang, S., Engineering Tunable Dual Functional Protein Cage Nanoparticles using Bacterial Superglue. Biomacromolecules, 2018, 19, 2896-2904.

10. Moon, H., Bae, Y., Kim, H. and Kang, S., Plug-and-Playable Fluorescent Cell Imaging Modular Toolkits Using the Bacterial Superglue, SpyTag/SpyCatcher. Chem. Comm., 2016, 52, 14051-14054.

11. Min, J.*, Song, E. K.*, Kim, H., Kim, K. T., Park, T. J. and Kang, S., A Recombinant Secondary Antibody Mimic as a Target-specific Signal Amplifier and an Antibody Immobilizer in Immunoassays. Sci. Rep. 2016, 6, 24159.

12. Song, Y. K.*, Kang, Y. J.*, Jung, H., Kim, H., Kang, S. and Cho, H. J., Lumazine Synthase Protein Nanoparticle-Gd(III)-DOTA Conjugate as a T1 contrast agent for high-field MRI. Sci. Rep. 2015, 5, 15656.

13. Moon, H., Lee, J., Kim, H., Heo, S., Min, J. and Kang, S., Genetically Engineering Encapsulin Protein Cage Nanoparticle as a SCC-7 Cell Targeting Optical Nanoprobe. Biomater. Res., 2014, 18,21.

그 외

1. Ryu, J-H., Oh, J. Y., Kim, H., Kim, C., Kang, S., “Fusion protein comprising glutathione-S-transferase and protein binding to target cell or target protein and uses thereof”, Korean Patent No. 1021122690000 (2020)

2. Ryu, J-H., Oh, J. Y., Kim, H., Kim, C., Kang, S., “HER2-GST-CPT complex, and pharmaceutical composition for preventing or treating cancer comprising the same”, Korean Patent No. 1021144470000 (2020)

3. Ryu, J-H., Oh, J. Y., Kim, H., Kim, C., Kang, S., “EGFR-GST-drug complex, and pharmaceutical composition for preventing or treating cancer comprising the same”, Korean Patent No. 1021144450000 (2020)'