학력

서울대학교 약학대학 제약학과

교육 및 연구경력

· Ph.D., Pharmaceutics, College of Pharmacy, Seoul National University
· Leader, AmorePacific Corporation R&D Unit, Amorepacific Corp. 
· Post-doctorate, Department of Chemistry, University of Massachusetts
· Research Professor, College of Medicine, Korea University

기타 및 학술관련 경력

· 한국약제학회 간사 (Financial manager, The Korean Society of Pharmaceutical Science and Technology)
· 대한화장품학회 회원 (Member, The Society of Cosmetic Scientists of Korea)

연구 관심 분야

· Therapeutic Biologics and Bioactives (Gene therapeutics, cell therapeutics, and peptide/protein therapeutics)
· Drug Delivery System, Drug Development
· Cosmetics/Skin biology
· Interdisciplinary, Translational Research 

강의 분야

· Biology (Undergraduate course)
· Process Validation (Undergraduate course)
· Biochemistry (Undergraduate course)
· Physiology (Undergraduate course)
· Biopharmaceutics, Drug Delivery System (Graduate course)

저서 및 주요 논문

SCI/SCIE peer-reviewed 2010-2021

1.  Lim H, jin S, Jeong Y, Kim S, Jang D, Kim ST. Preparation of hydroxypropyl-β-cyclodextrin-incorporated liposomes and evaluation of their rapid release property. J Ind Eng Chem. 2021 in press 

2. Choi SA, Park EJ, Kim YH, Jee JP, Kim ST, Jang DJ, Min KA, Cho KH. Screening of electrolyte complexes formed between dextran sulfate and amine structures of small-molecule drugs. J Nanosci Nanotechnol. 2021, 21(7), 3679-3782.  

3.  Hwang Y, Cho KH, Kim H, Kim H, Kim ST, Lee JG, Cheon SH, Choi S, Park HJ, Jang J, Choi S, Lee K, Park SY, Jang D. Surface activity and emulsifying effect of nontoxic starch nanocrystal. J Nanosci Nanotechnol. 2021, 21(7), 4051-4054

4.  Cheon S, Park S, Sung J, Lee JG, Choi S, Jang J, Kim H, Kim ST, Jeong S, Lee K, Jang D. Preparation and evaluation of nanostructured lipid nanocarrier for topical delivery of velutin: synthetic tyrosinase inhibitor. J Nanosci Nanotechnol. 2021, 21(7), 4093-4097

5.  Lim H, Kwon D, Park PJ, Bin B, Kim S, Park SY, Cho KH, Jang D, Kim ST. Topical delivery of nanosized hydroxycitric acid enriched extract-loaded ethosomes for suppreesion of lipid droplet deposition. J Nanosci Nanotechnol. 2021, 21(7), 4089-4092

6. Jo H, Cha B, Kim H, Brito S, Kwak BM, Kim ST, Bin B, Lee M. α-Pinene enhances the anticancer activity of natural killer cells via ERK/AKT pathway. Int J Mol Sci., 2021, 22(2), 656. (Impact factor=4.556)

7. Choi KH, Kim ST, Bin B, Park PJ. Effect of konjac glucomannan (KGM) on the reconstitution of the dermal enviroment against UVB-induced condition. Nutrients 2020, 12(9), 2779. 

8. Heo E, Park SY, Kim H, Sung J, Kwon HJ, Jee J, Maeng M, Cho KH, Kim ST, Kim YC, Choi S, Jang D. Optimization of hydroxypropyl methyl cellulose and dextrin in development of dried nanosuspension for poorly water-soluble drug. J Nanosci Nanotechnol. 2020, 20(9), 5813-5818. 

9. Park PJ, Kim ST. Caveolae-associated protein 3 (Cavin-3) influences adipogenesis via TACE-mediated Pref-1 shedding. Int J Mol Sci. 2020, 21(14), 5000. 

10. Kim YH, Kim Y, Kim JY, Byeon J, Maeng H, Kim ST, Min KA, Jang D, Cho KH. Preparation and characterization of tenofovir disoproxil-loaded enteric microparticle. J Nanosci Nanotechnol. 2020, 20(9), 5796-5799. 

11. Ryu K, Park PJ, Kim S, Bin B, Jang D, Kim ST. Topical delivery of coenzyme Q10-loaded microemulsion for skin regeneration, Pharmaceutics 2020, 12(4), 332. 

12. Kim W, Lee EJ, Bae I, Myoung K, Kim ST, Park PJ, Lee K, Pham AV, Ko J, Oh SH, Cho E. Lactobacillus plantarum-derived extracellular vesicles induce anti-inflammatory M2 macrophage polarization in vitro. J Extracell Vescles 2020, 9(1), 1793514. 

13. Heo E, Park SY, Kim H, Sung J, Kwon HJ, Jee J, Maeng H, Cho KH, Kim ST, Kim YC, Choi S, Jang D. Optimization of HPMC and dextrin in development of dried nanosuspension for poorly water-soluble drug. J Nanosci Nanotechnol. 2019, 20(9), 5813-5818

14. Maeng HJ, Yoon JH, Chun KH, Kim ST, Jang DJ, Park JE, Kim YH, Kim SB, Kim YC. Metabolic Stability of D-Allulose in Biorelevant Media and Hepatocytes: Comparison with Fructose and Erythritol. Foods. 2019, 8(10), 48. 

15. Choi SU, Kim ST, Han DG, Hwang YH, Lee KY, Kim DU, Cho KH, Park SY, Kim HC, Kim SB, Jang DJ. Comparative Assessment of Biological Activities of Mistletoes for Cosmetic Applications: Viscum Album Var. Coloratum (Kom.) Ohwi and Loranthus Tanakae Franch. & Sav. J Cosmet Sci. 2019, 70(5), 235-245. 

16. Lee MG, Choi MA, Chae S, Kang MA, Jo H, Baek JM, In KR, Park H, Heo H, Jang D, Brito S, Kim ST, Kim DO, Lee JS, Kim JR, Bin BH. Loss of the dermis zinc transporter ZIP13 promotes the mildness of fibrosarcoma by inhibiting autophagy. Sci Rep. 2019, 9(1), 15042 

17. Park PJ, Rha CS, Kim ST. Theaflavin-enriched fraction stimulates adipogenesis in human subcutaneous fat cells. Int J Mol Sci. 2019, 20(8). pii: E2034. 

18. Kim ST, Park T. Acute and Chronic Effects of cocaine on cardiovascular health. Int J Mol Sci. 2019, 20(3). pii: E584. 

19. Do YS, Cho KH, Kim HC, Kwon JY, Kim ST, Park SY, Kim YH, Kim JE, Park YJ, Maeng HJ, Jang DJ. Preparation of silica microparticles as volatile material carrier and their sustained-release property. J Nanosci Nanotechnol. 2019, 19(2):1188-1191. 

20. Kim HI, Jee JP, Kim ST, Kang D, Kim YC, Kim C, Park SY, Lee HM, Cho KH, Kim DY, Choi SU, Jang DJ. Preparation and characterization of celecoxib nanosuspension using bead milling. J Nanosci Nanotechnol. 2019, 19(2):1184-1187. 

21. Cho KH, Jee J, Yang D, Kim ST, Kang D, Kim D, Sim T, Park SY, Kim K, Jang D. Improved dissolution and oral bioavailability of celecoxib by a dry elixir system. J. Nanosci Nanotechnol, 2018, 18(2):1482-1486. 

22. Bin BH, Seo J, Kim ST. Function, structure, and transport aspects of ZIP and ZnT Zinc transporters in immune cells. J Immunol Res. 2018, Oct 2;2018:9365747. 

23. Kim Y, Kim ST, Jee J, Kim D, Kang D, Kim K, Park SY, Sim T, Cho KH, Jang D. Removing control of cyclodextrin-drug complexes using high affinity molecule, J Nanosci Nanotechnol, 2018, 18(2):898-901. 

24. Elci SG, Yesilbag Tonga G, Yan B, Kim ST, Kim CS, Jiang Y, Saha K, Moyano DF, Marsico ALM, Rotello VM, Vachet RW. Dual-mode mass spectrometric imaging for determination of in vivo stability of nanoparticle monolayers. ACS Nano, 2017, 11(7):7424-7430. 

25. Le NDB, Yesilbag Tonga G, Mout R, Kim ST, Wille ME, Rana S, Dunphy KA, Jerry DJ, Yazdani M, Ramanathan R, Rotello CM, Rotello VM. Cancer cell discrimination using host-guest "doubled" arrays. J Am Chem Soc 2017, 139(23):8008-8012. 

26.Lee K, Choi GS, Kim TW, Kwan Cho KH, Kang D, Kim ST, Jang D. Modeling and optimization of dough properties using response surface design. Food Engineer Prog, 2017, 21(2):132-137.

27. Bin BH, Kim ST, Bhin J, Lee TR, Cho EG. Synergistic effect of maltose for enhancing anti-melanogenic activity of acarbose. Arch Dermatol Res 2016 309(3):217-223. 

28. Hou S, Tang R, Kim ST, Jiang Z, Vachet R, Rotello VM. Quantitative mass spectrometric differentiation of cell surface-bound and internalized nanoparticles. ACS Nano. 2016 10(7):6731-6736. 

29. Elci SG, Jiang Y, Yan B, Kim ST, Saha K, Moyamo DF, Yesilbag Tonga G, Jackson LC, Rotello VM, Vachet RW. Surface charge controls the suborgan biodistributions of gold nanoparticles. ACS Nano. 2016 10(5):5536-5542. 

30. Bin BH, Kim ST, Bhin J, Lee TR, Cho EG. The development of sugar-based anti-melanogenic agents. Int J Mol Sci. 2016 17(4).583.

31. Kim ST, Jeong Y, Jiang Y, Duncan B, Kim CS, Saha K, Yeh Y, Yan B, Tang R, Hou S, Kim C, Park M, Rotello VM. Nanoparticle-dendrimer hybrid nanocapsules for therapeutic delivery. Nanomedicine. 2016 11(12):1571-1578. 

32. Elci SG, Yan B, Kim ST, Saha K, Jiang Y, Klemmer GA, Moyano DF, Tonga GY, Rotello VM, Vachet RW. Quantitative imaging of 2 nm monolayer-protected gold nanoparticle distributions in tissues using laser ablation inductively-coupled plasma mass spectrometry (LA-ICP-MS). Analyst. 2016 141(8):2418-2425. 

33. Bin BH, Kim D, Kim N, Choi E, Bhin J, Kim ST, Gho YS, Lee A, Lee TR, Cho EG. Fibronectin-containing extracellular vesicles protect melanocytes against ultraviolet radiation-induced cytotoxicity. J Invest Dermatol. 2016 136(5):957-966.

34. Saha K, Rahimi M, Yazdani M, Kim ST, Moyano DF, Hou S, Das R, Mout R, Rezaee F, Mahmoudi M, Rotello VM. Regulation of macrophage recognition through the interplay of nanoparticle surface functionality and protein corona. ACS Nano. 2016 10(4):4421-4430. 

35. Tonga GY, Jeong Y, Duncan B, Mizuhara T, Mout R, Das R, Kim ST, Yeh YC, Yan B, Hou S, Rotello VM. Supramolcular regulation of bioorthogonal catalysis in cells using nanoparticle-embedded transition metal catalysts. Nat Chem. 2015 7(7):597-603. 

36. Duncan B, Li X, Landis RF, Kim ST, Gupta A, Wang LS, Ramanathan R, Tang R, Boerth JA, Rotello VM. Nanoparticle-stabilized capsules for the treatment of bacterial biofilms. ACS Nano. 2015 9(8):7775-7782. 

37. Kim C, Tonga GY, Yan B, Kim CS, Kim ST, Park MH, Zhu Z, Duncan B, Creran B, Rotello VM. Regulating exocytosis of nanoparticles via host-guest chemistry. Org Biomol Chem. 2015 13(8):2474-2479. 

38. Ding Y, Jiang Z, Saha K, Kim CS, Kim ST, Landis RF, Rotello VM. Gold nanoparticles for nucleic acid delivery. Mol Ther. 2014 22(6):1075-1083. 

39. Kim ST, Yeh YC, Tang R, Yan B, Rotello VM. Insulin-Based Regulation of glucose-functionalized nanoparticle uptake in muscle cells. J Mater Chem B Mater Biol Med. 2014. (doi: 10.1039/C4TB00608A.) 

40. Kim ST, Park MH, Rana S, Solfiell D, Jeong Y, Duncan B, Yan B, Aksoy B, Rotello VM. Replenishable dendrimer-nanoparticle hybrid membranes for sustained release of therapeutics. Nanoscale. 2013 5(17):7805-7808. 

41. Kim ST, Saha K, Kim C, Rotello VM. The role of surface functionality in determining nanoparticle cytotoxicity. Acc Chem Res. 2013 46(3):681-691. 

42. Kim ST, Saha K, Yan B, Miranda OR, Alfonso FS, Shlosman D, Rotello VM. Surface functionality of nanoparticles determines cellular uptake mechanisms in mammalian cells. Small. 2013 9(2):300-305

43. Yan B, Kim ST, Kim CS, Saha K, Moyano DF, Xing Y, Jiang Y, Roberts AL, Alfonso FS, Rotello VM, Vachet RW. Multiplexed imaging of nanoparticles in tissues using laser desorption/ionization mass spectrometry. J Am Chem Soc. 2013 135(34):12564-12567. 

44. Jang D, Kim ST, Oh E, Ban E. Enhanced oral bioavailability and controlled release of dutasteride by a novel dry elixir. Biomed Mater Eng. 2013 23:S591-599. 

45. Jang D, Kim ST, Lee K, Oh E. Improved bioavailability and anti-asthmatic efficacy of poorly soluble curcumin-solid dispersion granules obtained using fluid bed granulation. Biomed Mater Eng. 2013 23:S433-449. 

46. Jang D, Kim ST, Oh E, Lee K. Enhanced oral bioavailability and anti-asthmatic efficacy of curcumin using redispersible dry emulsion. Biomed Mater Eng. 2013 23:S957-970. 

47. Kim ST, Chompoosor A, Yeh YC, Agasti SS, Solfiell DJ, Rotello VM. Dendronized gold nanoparticles for siRNA delivery. Small. 2012 8(21):3253-3256. 

48. Ban E, Shin H, Kim ST, Kim CK. Determination of 3alpha-hydroxytibolone by LC/MS/MS with electrospray ionization method and its application to bioequivalence study in human plasma. J Pharm Invest. 2012 42: 353-360. 

49. Hong YJ, Kim N, Lee K, Sonn CH, Lee JE, Kim ST, Baeg IH, Lee KM. Korean red ginseng (Panax ginseng) ameliorates type 1 diabetes and restores immune cell compartments. J Ethnopharmacol. 2012 144(2):225-233. 

50. Min JH, Kim ST, Lee JS, Kim K, Wu JH, Jeong J, Song A, Lee KM, Kim YK. Labelling of macrophage cell using biocompatible magnetic nanoparticles. J Appl Phys 109(7), 07B309. 

51. Kim TJ, Kim N, Kang HJ, Kim EO, Kim ST, Ahn HS, Bluestone JA, Lee KM. FK506 causes cellular and functional defects in human natural killer cells. J Leukoc Biol 2010, 88(6), 1089-1097. 

52. Hong SJ, Kim ST, Kim TJ, Kim EO, Ahn CM, Park JH, Kim JS, Lee KM, Lim DS. Arterioscler Thromb Vasc Biol 2010, 30(12), 2655-2665. 

53. Kim ST, Kim DJ, Kim TJ, Seo DW, Kim TH, Lee SY, Kim K, Lee KM, Lee SK. Novel streptavidine-functionalized silicon nanowire arrays for CD4+ T lymphocyte separation. Nano Lett. 2010, 10(8), 2877-2883. 

54. Park TH, Kim ST, Park JS, Choi HG, Kim HT, Kim CK. Effect of zinc oxide on the rheological and mucoadhesive properties of poloxamer 407-based mucoadhesive thermosensitive gel. Drug Dev Ind Pharm. 2010, 36(12), 1436-1443. 

55. Kim EO, Kim TJ, Kim N, Kim ST, Kumar V, Lee KM. Homotypic cell to cell cross-talk among human natural killer cells reveals differential and overlapping roles 2B4 and CD2. J Biol Chem. 2010, 285(53), 41755-41764. 

56. Kim ST, Park J, Kim HT, Kim CK. Simple determination of erdosteine in human plasma using high performance liquid chromatography. J Liq Chromatogr Rel Technol 2010, 33(13), 1319-1327.

Patent
1. Composition comprising lactic acid bacteria derived extracellular vesicles for preventing hair loss or promoting hair growth. Inventor: Kim ST, Lee YH, Shin SH, Hwang K, Cho EG, Lee TR. (KP application 1020150137862)

2. Ant-inflammatory composition comprising extracellular vesicles derived from yeast. Inventor: Kim ST, Cho EG, Lee TR, Kim SR, Hong KH, Gho YS. (KP application)

3. Composition for promoting angiogenic activity comprising exosome-mimetic nanovesicles derived from adult stem cells. Inventor: Kim ST, Cho EG, Bin BH, Lee TR, Kim SR, Hong KH, Gho YS (KP application)

4.Composition for skin whitening and method for screening the skin whitening materials. Inventor: Bin BH, Cho EG, Choi E, Kim ST, Choi SY, Lee TR. (KP application 1020150093049)　

5.Cell separation chip using silicon nanowire. Inventors: Lee SK, Kim DJ, Lee SY, Lee KM, Kim ST. Korea Patent number: KP 1020100029381

Book
1.T. A. Brown 생화학 포커스 (공역) ㈜ 바이오사이언스출판